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levels of immune checkpoints are modulated by treatment with CPI-444
Molecular Weight: 500
25(10):2524-33
TAMR-1 and 182R-6[1]
Marsilje TH
LDN193189 Tetrahydrochloride - CAS# 2310134-98-4 Catalog No.:M6899-2 levels of immune checkpoints areLDN193189 Tetrahydrochloride, CAS No. 2310134 98 4, is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50500 nM). Product information CAS Number: 2310134 98 4 Molecular Weight: 552. 33 Formula: C25H26Cl4N6 Chemical Name: LDN193189 Tetrahydrochloride Smiles: Cl. Cl. Cl. Cl. C1CNCCN1C1C=CC(=CC=1)C1=CN2N=CC(=C2N=C1)C1=CC=NC2=CC=CC=C21
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