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PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1
Ledipasvir has GT1a and 1b EC50 values of 31 and 4 pM
Hofmann-Wellenhof R
InChi: InChI=1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3
CHMFL-ABL-053 showed less potent to DDR1 (IC50: 292 nM) and DDR2 (IC50: 457 nM)
26-Deoxycimicifugoside ibendol PD-1/PD-L1-IN 5 is a PD-1/PD-L126 Deoxycimicifugoside is a triterpene xylosides isolated from Cimicifuga racemosa. Product information CAS Number: 214146 75 5 Molecular Weight: 658. 82 Formula: C37H54O10 Chemical Name: (1R,1'S,2S,3'R,4'R,5R,5'R,6'R,10'S,12'S,16'R,18'S,21'R) 4',5,6',12',17',17' hexamethyl 18' {[(2S,3R,4S,5R) 3,4,5 trihydroxyoxan 2 yl]oxy} 3,6,9' trioxaspiro[bicyclo[3. 1. 0]hexane 2,8' hexacyclo[11. 9. 0. 0,. 0,. 0,. 0,]docosan] 13' en 3' yl acetate Smiles:
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